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Laboratory Monitoring of Coagulation

Release Date: August 7, 2006

Expiration Date: August 7, 2007

Estimated time to complete this Activity: 1 hour

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Overview

Traditional coagulation assays, such as prothrombin time and activated partial thromboplastin time, do not provide information on important aspects of the kinetics of clot formation, and as a result, these assays do not accurately describe the quality of the final thrombus or predict the response to treatment. New technologies that more accurately assess and monitor clot formation are being developed. Accurate monitoring of coagulation, particularly in terms of treating and preventing thrombosis, is becoming increasingly important because of the greater use of combination regimens of anticoagulants, antiplatelets, and/or thrombolytic agents, and newer antithrombotics. These regimens are associated with an increased risk of bleeding, and considerable variability exists in the response to these drugs. This slide presentation will describe the limitations of currently available assays in monitoring coagulation and will review emerging methods of assessing clot kinetics.

Target Audience

Laboratory Monitoring of Coagulation is intended to provide transfusion specialists, hematologists, and other healthcare professionals with an overview of current and evolving methods of assessing coagulation.

Learning Objectives

After completing this continuing medical education (CME) activity, participants should be able to:

• Describe the limitations of currently available coagulation assays
• Describe three emerging assays for monitoring the kinetics of clot formation
• Evaluate emerging technology to assess platelet activation

Accreditation Statement

This activity has expired.

Designation Statement

This activity has expired.

How to Get Credit

This activity has expired.

Faculty Disclosure

It is the policy of the FCG Institute for Continuing Education that all faculty participating in continuing medical education activities are expected to disclose to the program audience (1) any real or apparent conflict(s) of interest related to the content of their presentation and (2) discussion of unlabeled or unapproved uses of drugs or medical devices. Faculty disclosure statements can be found with their biographical sketches.

Conflict of Interest Resolution

When individuals in a position to control or influence the development of the content have reported Financial Relationships with one or more commercial interests, The FCG Institute for Continuing Education utilizes a process to identify and resolve potential conflicts to ensure that the content presented is free of commercial bias. The content of this presentation was vetted through The Institute’s process of peer review and content validation and modified as required to meet this standard.

Notice About Investigational or Off-Label Use

This educational activity may include discussion of drugs or devices or uses of drugs and devices, that have not been approved by the FDA or have been approved by the FDA for specific uses only. It is the responsibility of the physician to determine the FDA clearance status of each drug or device he or she wishes to use in clinical practice. The FCG Institute for Continuing Education is committed to the free exchange of medical education. Inclusion of any product or device discussion, including discussion of investigational or off-label uses, does not imply endorsement by The Institute of the uses, products, or techniques presented.

Disclaimer

This CME/CE activity is designed for use by healthcare professionals for educational purposes only. The information and opinions expressed by the faculty are their own and do not necessarily reflect those of The FCG Institute. The FCG Institute for Continuing Education does not define a standard of care, nor does it intend to dictate an exclusive course of management but presents through the educational activities it sponsors recognized methods and techniques of clinical practice for consideration by physicians and other healthcare providers for incorporation into their practices. Participants should use their own clinical judgment before applying information, whether provided here or by others, for any professional use.

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Sponsored by: The FCG Institute for Continuing Education

The FCG Institute for Continuing Education
gratefully acknowledges an educational grant from
Novo Nordisk Inc. in support of this Web Site