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Rare Bleeding Disorders

Release Date: September 14, 2006

Expiration Date: September 14, 2007

Estimated time to complete this Activity: 45 minutes

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Overview

Congenital bleeding disorders are rare and range from hemophilia A and B to deficiencies in fibrinogen or coagulation factors such as II, V, VII, X, or XIII. Because these conditions affect very small numbers of individuals, finding effective treatment options is limited by the lack of adequate numbers of patients available for clinical trials. Other factors, such as the variable symptoms and clinical outcomes in rare bleeding disorders, the cost of conducting these trials, and regulatory considerations, also hamper the development of effective therapies. This slide presentation will provide an overview of the prevalence of rare bleeding disorders and their associated genotyping. Diagnosis of these conditions, their clinical manifestations, and treatment strategies, including prophylactic regimens, will be discussed. The presentation also will describe a North American registry for rare bleeding disorders that aims to serve as an important resource for basic scientists and clinicians.

Target Audience

Rare Bleeding Disorders is intended to describe to transfusion specialists, hematologists, and other healthcare professionals the incidence, clinical manifestations, and management of rare bleeding disorders.

Learning Objectives

After completing this continuing medical education (CME) activity, participants should be able to:

• List the prevalence and genotyping frequency of rare bleeding disorders
• Describe the clinical manifestations of rare bleeding disorders
• Evaluate current treatment options, including prophylactic strategies
• Describe various treatment-related complications

Accreditation Statement

This activity has expired.

Designation Statement

This activity has expired.

How to Get Credit

This activity has expired.

Faculty Disclosure

It is the policy of the FCG Institute for Continuing Education that all faculty participating in continuing medical education activities are expected to disclose to the program audience (1) any real or apparent conflict(s) of interest related to the content of their presentation and (2) discussion of unlabeled or unapproved uses of drugs or medical devices. Faculty disclosure statements can be found with their biographical sketches.

Conflict of Interest Resolution

When individuals in a position to control or influence the development of the content have reported Financial Relationships with one or more commercial interests, The FCG Institute for Continuing Education utilizes a process to identify and resolve potential conflicts to ensure that the content presented is free of commercial bias. The content of this presentation was vetted through The Institute’s process of peer review and content validation and modified as required to meet this standard.

Notice About Investigational or Off-Label Use

This educational activity may include discussion of drugs or devices or uses of drugs and devices, that have not been approved by the FDA or have been approved by the FDA for specific uses only. It is the responsibility of the physician to determine the FDA clearance status of each drug or device he or she wishes to use in clinical practice. The FCG Institute for Continuing Education is committed to the free exchange of medical education. Inclusion of any product or device discussion, including discussion of investigational or off-label uses, does not imply endorsement by The Institute of the uses, products, or techniques presented.

Disclaimer

This CME/CE activity is designed for use by healthcare professionals for educational purposes only. The information and opinions expressed by the faculty are their own and do not necessarily reflect those of The FCG Institute. The FCG Institute for Continuing Education does not define a standard of care, nor does it intend to dictate an exclusive course of management but presents through the educational activities it sponsors recognized methods and techniques of clinical practice for consideration by physicians and other healthcare providers for incorporation into their practices. Participants should use their own clinical judgment before applying information, whether provided here or by others, for any professional use.

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Sponsored by: The FCG Institute for Continuing Education

The FCG Institute for Continuing Education
gratefully acknowledges an educational grant from
Novo Nordisk Inc. in support of this Web Site