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Effective Hemostasis: The Balance Between Bleeding and Clotting

Release Date: October 16, 2006

Expiration Date: October 16, 2007

Estimated time to complete this Activity: 1.25 hours

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Overview

In vivo findings indicate that the hemostatic response to vascular damage involves a complex series of events that requires the interaction of the activated endothelial cell with blood and vascular cellular elements and blood plasma proteins, such as coagulation factors II, V, VII, VIII, IX, and X. One of the major challenges in hemostasis is balancing the activities of procoagulant and antifibrinolytic components against anticoagulant and fibrinolytic components. Achieving this balance is complicated by the newer and more potent medications that are being used on all patients, including those who undergo surgery. This presentation will provide an overview of cellular controlled hemostasis, including the role of activated endothelial cells, platelets, and coagulation proteins. The hemostatic fluctuations in various patients, including those undergoing surgery or patients with bleeding disorders, will be described, and the use of various therapeutic strategies to achieve hemostasis will be reviewed.

Target Audience

Effective Hemostasis: The Balance Between Bleeding and Clotting is intended to provide transfusion specialists, hematologists, and other healthcare professionals with an overview of the challenges involved in balancing bleeding and clotting processes to achieve hemostasis.

Learning Objectives

After completing this continuing medical education (CME) activity, participants should be able to:

• Describe the role of endothelial cells, platelets, and coagulation proteins in hemostasis
• Identify the hemostatic challenges in surgery, trauma, and congenital bleeding disorders
• Evaluate the use of therapeutic agents in the prevention and management of bleeding and thrombosis

Accreditation Statement

This activity has expired.

Designation Statement

This activity has expired.

How to Get Credit

This activity has expired.

Faculty Disclosure

It is the policy of the FCG Institute for Continuing Education that all faculty participating in continuing medical education activities are expected to disclose to the program audience (1) any real or apparent conflict(s) of interest related to the content of their presentation and (2) discussion of unlabeled or unapproved uses of drugs or medical devices. Faculty disclosure statements can be found with their biographical sketches.

Conflict of Interest Resolution

When individuals in a position to control or influence the development of the content have reported Financial Relationships with one or more commercial interests, The FCG Institute for Continuing Education utilizes a process to identify and resolve potential conflicts to ensure that the content presented is free of commercial bias. The content of this presentation was vetted through The Institute's process of peer review and content validation and modified as required to meet this standard.

Notice About Investigational or Off-Label Use

This educational activity may include discussion of drugs or devices or uses of drugs and devices, that have not been approved by the FDA or have been approved by the FDA for specific uses only. It is the responsibility of the physician to determine the FDA clearance status of each drug or device he or she wishes to use in clinical practice. The FCG Institute for Continuing Education is committed to the free exchange of medical education. Inclusion of any product or device discussion, including discussion of investigational or off-label uses, does not imply endorsement by The Institute of the uses, products, or techniques presented.

Disclaimer

This CME/CE activity is designed for use by healthcare professionals for educational purposes only. The information and opinions expressed by the faculty are their own and do not necessarily reflect those of The FCG Institute. The FCG Institute for Continuing Education does not define a standard of care, nor does it intend to dictate an exclusive course of management but presents through the educational activities it sponsors recognized methods and techniques of clinical practice for consideration by physicians and other healthcare providers for incorporation into their practices. Participants should use their own clinical judgment before applying information, whether provided here or by others, for any professional use.

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Sponsored by: The FCG Institute for Continuing Education

The FCG Institute for Continuing Education
gratefully acknowledges an educational grant from
Novo Nordisk Inc. in support of this Web Site